diff --git a/miniz.h b/miniz.h
index 17f2c3b..90e4860 100644
--- a/miniz.h
+++ b/miniz.h
@@ -170,6 +170,8 @@
 #define MINIZ_LITTLE_ENDIAN 0
 #endif
 
+/* Set MINIZ_USE_UNALIGNED_LOADS_AND_STORES only if not set */
+#if !defined(MINIZ_USE_UNALIGNED_LOADS_AND_STORES)
 #if MINIZ_X86_OR_X64_CPU
 /* Set MINIZ_USE_UNALIGNED_LOADS_AND_STORES to 1 on CPU's that permit efficient integer loads and stores from unaligned addresses. */
 #define MINIZ_USE_UNALIGNED_LOADS_AND_STORES 1
@@ -177,6 +179,7 @@
 #else
 #define MINIZ_USE_UNALIGNED_LOADS_AND_STORES 0
 #endif
+#endif
 
 #if defined(_M_X64) || defined(_WIN64) || defined(__MINGW64__) || defined(_LP64) || defined(__LP64__) || defined(__ia64__) || defined(__x86_64__)
 /* Set MINIZ_HAS_64BIT_REGISTERS to 1 if operations on 64-bit integers are reasonably fast (and don't involve compiler generated calls to helper functions). */